The Pearl River International Forum on Bone & Joint Diseases 2018
& The 1st Osteoarthritis Research Society International (OARSI) Guangzhou Satellite Meeting
December 15, 2018 Guangzhou, China
Osteoarthritis Research Society International (OARSI)
Rheumatology & Immunology Committee of Association of Medical Exchange Across the Taiwan Straits
ORGANIZED BY: Zhujiang Hospital of Southern Medical University
International Chinese Osteoarthritis Research Society (ICOARS)
Rheumatology Branch of Guangdong Medical Association
Orthopedics Branch of Guangdong Medical Association
Beijing Trust Medical Media
DATE：December 15 to 16, 2018
FORUM VENUE: Guangzhou Baiyun International Convention Center
On behalf of the Organising Committee, we would like to invite you to the Pearl River International Forum On Bone & Joint Diseases 2018 and the 1st Osteoarthritis Research Society International (OARSI) Guangzhou Satellite Meeting, on 15-16, December 2018.
OARSI is the premier international organization for scientists and health care professionals focused on the prevention and treatment of osteoarthritis through the promotion and presentation of research, education and the worldwide dissemination of new knowledge. China, with leading population in the world, has the largest number of osteoarthritis patients worldwide. The prevalence of osteoarthritis in China accounts for about 10% of the total population, reaching at an estimated number of 100 million. Thus, we sincerely invite you to participate in the first OARSI Satellite Meeting in China, helping promote knowledge in OA research and care.
This conference will be held in Guangzhou (Canton), China, focusing on advances in clinical and basic research of bone and joint related diseases. It will have four sessions including “Clinical epidemiological research in bone and joint diseases”, “Mechanisms underlying bone and joint diseases”, “Early detection and diagnosis of bone and joint diseases”, and “Therapeutic potentials for bone and joint diseases”.
Guangzhou, the forerunner of China's reform and opening up, is blessed with a profound history dating back two thousand years, and boasts the unique and splendid culture of Southern China. Hence, Guangzhou will not only make a perfect venue for the meeting, but will also offer a chance for participants to explore Chinese culture, traditions, as well as China's unique development.
We promise Guangzhou will leave you with unforgettable memories. You will be delighted by discovering the charms of this ancient and modern city. We eagerly look forward to meeting you in Guangzhou in 2018!
Changhai Ding, Professor and Director of Clinical Research Centre, Zhujiang Hospital, Southern Medical University
Ali Mobasheri, President-elect of OARSI, Professor of University of Surrey, UK
Xiaofeng Zeng, President of Chinese Rheumatology Association, Director of Rheumatology, Beijing Union Medical College Hospital
Consultants: Academician Zihe Rao, Academician Kerong Dai
Honorary Chairs: Qian Wang, Zhanguo Li
Conference Chairs: Changhai Ding, Ali Mobasheri (UK), Xiaofeng Zeng
Executive Chairs： Lie Dai, Cibo Huang, David Hunter (Australia), Jianhao Lin, Qi Li, Huiyong Shen, Qinghong Yu
Committee Members：Xiaochun Bai, Daozhang Cai, Jieruo Gu, Yongqiang Hao, Qing Jiang, Anmin Jin, Guanghua Lei, Xiaojuan Li (USA), Xiaomei Leng, Lijun Lin, Hsiao-yi Lin, Shaoxiong Min, Limin Rong, Xisheng Weng, Jianhua Xu, Zhengang Zha, Weiya Zhang (UK), Zhiyi Zhang, Xuewu Zhang, Yuqing Zhang (USA)
Committee Secretaries：Zhaohua Zhu, Weiyu Han, Yuan Qu, Jia Li, Yu Liu, Jieli Chen
Special invited experts:
Prof. Joel Block, Editor-in-chief, Osteoarthritis and Cartilage, Rush University, USA
Prof. Flavia Cicuttini, Monash University, Australia
Prof Martin Englund, Lund University, Sweden
Prof. Ali Guermazi, Boston University, USA
Prof. David Hunter, University of Sydney, Australia
Prof. Rikard Holmdahl, Karolinska Institutet, Sweden
Prof. Virginia Kraus, Past President of OARSI, Duke University, USA
Prof. John Loughlin, Past President of OARSI, Newcastle University, UK
Prof. Anne-Marie Malfait, Rush University, USA
Prof. Ali Mobasheri, President-elect of OARSI, University of Surrey, UK
Zihe Rao, Ph.D, Prof., CASM
Prof. Rao is a Biophysicist and Structural Biologist, mainly engaged in the study of crystal or CryoEM structures of proteins and pathogens related to human infection, as well as in the development of innovative drug treatment.
Since 2003, Prof. Rao has been elected as a Member of Chinese Academy of Sciences, Academy of Sciences for Developing Countries and International Eurasian Academy of Sciences, a Fellow of Hertford College, University of Oxford and the Royal Society of Edinburgh, an Honorary Professor of University of Glasgow and Hong Kong Baptist University. From 2014-2017, Prof. Rao served as the President of International Union for Pure and Applied Biophysics (IUPAB). From 2006-2017, he served as the Chairman of Biophysics Society of China.
Orthopaedic Surgery and Orthopaedic Biomechanics
Prof. Dai is a Member of the Chinese Academy of Engineering, a tenured Professor and Doctorate supervisor, the Dean of Ninth Hospital Medical School affiliated to Shanghai Second Medical University, Director of Shanghai Medical Center of Joint Surgery and of the Bone and Joint Research Center, Director of Plant Engineering Research Center of Shanghai Jiao Tong University-Shanghai Second Medical University. Due to his outstanding achievement in the fields of medical application of shape-memory alloy, orthopaedic biomechanics and osteoporosis, he has won 21 prizes including Chinese National Invention Prize (Second Prize), National Science and Technology Prize, the First Prize granted by National Educational Committee, Shanghai Municipal Scientific and Technological Prize, and has got 9 patents. Moreover, he was awarded the first Shanghai Invention Prize, the Outstanding Visiting Scholar to Hong Kong in 1997 and Shanghai Medical Honorary Prize.
Prof Wang is currently the President of Zhujiang Hospital of Southern Medical University. He was former Vice President of Southern Medical University, and former Deputy President of Nanfang Hospital. Scholarly exchange at Nuffield Orthopedic Centre of Oxford University Hospital, St-Mary’s Hospital, University of California, Los Angles and Johns Hopkins University.
Dr. Li is a Professor of Rheumatology and the Director of Clinical Immunology Center at People’s Hospital, Peking University Medical School, and one of the best known rheumatologists in the country. He has been practicing clinical rheumatology for the last 30 years, and is very experienced in rheumatoid arthritis, systemic lupus erythematosus, Sjogren’s syndrome, ankylosing spondylitis and vasculitis. His research interests include the pathogenesis and immune therapy of rheumatoid arthritis, and early diagnosis and treatment for SLE and SS.
Changhai Ding, OARSI Board Member, Director of Clinical Research Center of Zhujiang Hospital of Southern Medical University, Professor at University of Tasmanian, Associate Director (International) of Menzies Institute for Medical Research, an Honorary Professor at the University of Sydney, and an Adjunct Professor at Monash University. Prof Ding has focused on the epidemiological and clinical studies in osteoarthritis and osteoporosis for almost 20 years, and has published over 300 papers in journals including JAMA, JAMA Internal Medicine, and Annals of the Rheumatic Diseases.
Director of Department of Rheumatology and Immunology at Peking Union Medical College Hospital, President of Chinese Rheumatology Association, President of Rheumatology and Immunology Branch of Chinese Medical Doctor Association. His research interests include pathogenesis and treatment of vasculitis, early diagnosis of rheumatoid arthritis and sicca syndrome.
President-elect of OARSI, University of Surrey, UK
Ali Mobasheri is Professor of Musculoskeletal Physiology and Associate Dean for Research and Enterprise in the Faculty of Health and Medical Sciences at the University of Surrey, UK. His main area of research is cartilage biology and osteoarthritis biomarkers. He currently co-ordinates the EU FP7 D-BOARD consortium funded by a 5.9 million Euro grant from the European Commission, which brings together leading European academic institutions and SMEs to focus on the identification, validation and qualification of new biomarkers for degenerative and inflammatory diseases of joints. He is also a participating member of the recently launched Applied Public-Private Research enabling OsteoArthritis Clinical Headway (APPROACH) consortium, which received a 7.5 million Euro grant from the European Commission’s Innovative Medicines Initiative. The overall objective of APPROACH is to phenotype OA patients in order to find the right patient for the right treatment. Ali’s track record of professional achievement is backed up by 180 primary peer-reviewed publications.
Lie Dai, Professor, Director, Department of Rheumatology, Sun Yat-Sen Memorial Hospital. Prof. Dai has worked on the clinical practice, basic research and medical education. As a rheumatologist, her major scientific interest is in arthritis, especially rheumatoid arthritis and gout. She is the first person who developed synovial biopsy and synovial histopathological research in China, which has contributed significantly to the clinical and basic research of arthritis. She is also a pioneer in developing systemic laboratory tests of crystal analysis, including diagnosing crystal-induced arthritis in China.
Cibo Huang, Director, Department of Rheumatology at Beijing Hospital, Deputy Director of Rheumatology and Immunology Branch of Chinese Medical Doctor Association, President of Association of Medical Exchange Across the Taiwan Straits. His research interests include pathogenesis and treatment of Sjogren's syndrome, osteoarthritis, lupus erythematosus, Behcet's disease, Lyme disease.
Jianhao Lin, M.D., Director, Department of Arthritis Clinic and Research Center at People’s Hospital, Peking University. Prof. Lin was a board member and is the Chairman of Asian Task of Osteoarthritis Research Society International (OARSI). He is one of founders of International Chinese Osteoarthritis Research Society (ICOARS). His expertise includes evaluation of the disorders of the joint, particularly the lower extremity joints, extensive experience in total hip and knee arthroplasty, actively involved in a population-based survey of knee osteoarthritis in Chinese population, with interests in the mechanics of osteoarthritis and joint reconstruction and replacement.
David Hunter, University of Sydney, Australia
Professor Hunter is a rheumatology clinician researcher whose main research focus has been clinical and translational research in osteoarthritis (OA). He is the Florance and Cope Chair of Rheumatology and Professor of Medicine at University of Sydney and the Royal North Shore Hospital and Consultant Rheumatologist at North Sydney Orthopaedic and Sports Medicine Centre. He is ranked as the worlds leading expert in osteoarthritis on Expertscape.com since 2014. He is on the editorial board for Arthritis and Rheumatology, Osteoarthritis and Cartilage, Arthritis Care and Research and part of the review committee for OA for the American College of Rheumatology, EULAR and OARSI scientific meetings. Dr. Hunter has over 400 peer reviewed publications in international journals, numerous book chapters, is the section editor for UpToDate Osteoarthritis and has co-authored a number of books, and recently completed his second book on self-management strategies for the lay public.
Qi Li, Dr. Li is a Professor of Orthopedics and the Director of Joint and Bone Disease Surgery at Zhujiang Hospital, Southern Medical University. He is very experienced in complicated diseases diagnosis and treatment. He is proficient in various modern joint surgery techniques such as arthroscopy, total knee arthroplasty, total hip arthroplasty, shoulder replacement and elbow replacement, especially experienced for multi-joint simultaneous replacement and artificial joint revision therapy.
Huiyong Shen, Director of Orthopedics Department at Sun Yat-Sen Memorial Hospital. Prof. Shen Huiyong is specializing in spinal surgery and spinal cord injury. He is also the first person in China who applies the method of cryopreservation to preserve human embryonic olfactory ensheathing cells, which not only reduces the immunogenicity of the cells but also provides the opportunity of emergency transplantation to patients in the future. He has published more than 100 pieces of academic papers and five professional books. He has won the research funds from foundations including the National Natural Science Foundation, National "973" Development Program, National "985" Program, the Guangdong Provincial Natural Science Foundation, and Guangzhou City Science and Technology Projects.
Qinghong Yu, M.D., Professor, Director, Department of Rheumatology at Zhujiang Hospital of Southern Medical University. Deputy Director of the Rheumatology and Immunology Branch of the Chinese Medical Bioimmunological Society, Deputy Director of the Chinese Society of Rehabilitation Medicine Rheumatology Branch. His research interests include the pathogenesis and immune therapy of rheumatoid arthritis, and early diagnosis and treatment for SLE, spinal arthritis.
Special invited experts:
Joel Block, Editor-in-chief, Osteoarthritis and Cartilage, Rush University, USA
Joel A. Block, MD, is the Willard L. Wood, MD, Professor of Rheumatology at Rush Medical College. He is Director of the Division of Rheumatology and Director of the Rush Center for Clinical Studies at Rush University Medical Center. He has served on numerous grant review panels for the NIH, Department of Defense, and multiple overseas governmental funding agencies, as well as domestic and foreign foundations. He is currently a member of the Board of Directors of the American College of Rheumatology and is an ex officio member of the Board of Directors of the Osteoarthritis Research Society International. He is a past chair of the Annual Meeting Planning Committee and the Committee on Education of the American College of Rheumatology. He serves as Editor in Chief of Osteoarthritis and Cartilage, and is on the Editorial Boards of the Journal of Orthopaedic Research and the Journal of Clinical Rheumatology. Block’s early research focused on cartilage biology and chondrocytic proteoglycans, and several of his human chondrocyte cell models remain in use in laboratories on four continents. His interests subsequently broadened to include the role of aberrant biomechanical loading in lower extremity osteoarthritis. He leads a large multidisciplinary group that studies osteoarthritis from a broad perspective, including joint tissue biology, physiology of pain and mechanical mediators of osteoarthritis progression, all with a focus on identifying novel therapeutic strategies.
Flavia Cicuttini, Monash University, Australia
Flavia’s current research includes using Magnetic Resonance Imaging to understand factors that affect joint cartilage in healthy and diseased states. Contributions to teaching include coordination and teaching Research Methods in the Master of Public Health, coordination of Epidemiology and Biostatistics by distance mode of delivery, and Medicine and Research for 4th year undergraduate medical students.
Martin Englund, Lund University, Sweden
Martin Englund at Clinical Epidemiology Unit, Orthopedics, Department of Clinical Sciences Lund, Lund University and Skåne University Hospital, is a Swedish epidemiologist and clinical investigator. Dr. Englund heads the Clinical Epidemiology Unit, Orthopedics at Lund University and also holds a position as adjunct professor at Boston University School of Medicine. His main research focus is the role of meniscus in early knee OA development as well as OA pathogenesis using translational research approaches and the societal burden of musculoskeletal disease.
Ali Guermazi, Boston University, USA
Dr. Guermazi is a French board-certified radiologist. Prior to joining Boston University, he was Director of the Osteoporosis and Arthritis Research Group (OARG) at University of California at San Francisco (UCSF) and then Director of Clinical Research at Synarc, Inc. in San Francisco. Dr. Guermazi interest is musculoskeletal diseases, in particular note are his scientific contributions in the diagnosis and disease progression assessment of osteoarthritis using MRI. His work has focused on identifying structural risk factors for developing and worsening osteoarthritis. Dr. Guermazi had been involved in developing several original and widely accepted radiological methods to assess osteoarthritis disease risk and progression, including the WORMS, BLOKS and MOAKS for the knee, HOAMS for the hip and fixed-flexion radiography for measuring joint space width. Dr. Guermazi has been involved as an MRI reader for the past 14 years in several large U.S. studies including the Health Aging and Body Composition (Health ABC) study, the Boston Osteoarthritis Knee study (BOKS), the Multi-center Osteoarthritis STudy (MOST), the Framingham study, Osteoarthritis Initiative (OAI), and other large NIH-funded studies, as well as several Pharmaceutical-sponsored clinical trials. He is author of over 275 peer-reviewed publications and Investigator on numerous research grants related to MRI reading for Osteoarthritis.
Rikard Holmdahl, a member of the Nobel Conference for the Nobel Prize in Medicine, International Leading Scientist, MD, PhD, is professor of Karolinska Institute of Medicine, is head of the Medical Immunology Center. The center consists of a laboratory and an animal model platform that is based on molecular mechanisms to study autoimmune and inflammatory diseases and is dedicated to the diagnosis and prevention of these diseases. Dr. Holmdahl has published peer reviewed papers in a number of leading journals including Nature, Nature Genetics, PNAS, Nature Medical, Science, Cell, journal of clinical investigation, The Journal of Experimental Medicine.
Virginia Kraus, Past President of OARSI, Duke University, USA
Virginia Byers Kraus, MD, PhD, is Professor of Medicine, Pathology, and Orthopaedic Surgery, and a faculty member of the Duke Molecular Physiology Institute in the Duke University School of Medicine. She is a practicing Rheumatologist with 20 years’ experience in Osteoarthritis research.
Dr. Kraus is past president of the Osteoarthritis Research Society International (OARSI); the premier organization focused on the prevention and treatment of osteoarthritis through the promotion and presentation of research, education, and the worldwide dissemination of new knowledge. She is co-PI of the OARSI/Foundation for NIH Osteoarthritis Biomarkers Consortium Project, which advances the validation and qualification of biomarkers for OA diagnosis, prognosis, and clinical trials. She also directs the Duke Biomarkers Shared Resource under the management of Janet Huebner.
John Loughlin, Past President of OARSI, Newcastle University, UK
Professor John Loughlin is a molecular and cell biologist with a background in genetics. In 2002 he was awarded a tenured lectureship at Oxford and in 2008 he moved to Newcastle University as Professor of Musculoskeletal Research.
Professor Loughlin’s laboratory focuses on the identification and characterization of those genes that confer risk towards the development and progression of OA. Through the application of powerful genome-wide association scans involving tens of thousands of OA patients, his group has identified a large number of OA susceptibility genes. His group’s efforts are directed toward comprehensive functional analysis of the associated variants within these genes, and in others that are emerging from ongoing scans. Professor Loughlin has published peer reviewed papers in a number of leading journals including Nature Genetics, PNAS, The Lancet, British Medical Journal, American Journal of Human Genetics, PLoS Genetics, Human Molecular Genetics, Journal of Biological Chemistry, Arthritis & Rheumatism, and Osteoarthritis and Cartilage.
Anne-Marie Malfait, Rush University, USA
Anne-Marie Malfait, MD PhD, is Professor of Internal Medicine and The George W. Stuppy, MD, Chair of Arthritis at Rush University in Chicago IL. Her early research training focused on cartilage metabolism in osteoarthritis. Her postdoctoral training at the Kennedy Institute of Rheumatology in London focused on the role of cytokines in inflammatory arthritis. Her group studies the relationship between joint damage and the neurobiological processes that underlie OA pain, with the long-term goal to develop more efficacious and safer analgesics and DMOADs. Anne-Marie is an Associate Editor for Osteoarthritis and Cartilage and for Arthritis and Rheumatology.
|The Peal River International Forum on Bone & Joint Diseases 2018
The 1st OARSI Guangzhou Satellite Meeting
|08:00-08:30||Opening Ceremony||Qian Wang, Xiaofeng Zeng, Ali Mobasheri, Cibo Huang, Jianhao Lin||Changhai Ding, Qinghong Yu|
|08:30-10:00||Epidemiological research in bone and joint diseases||Inflammation in Osteoarthritis: Cause or Effect||Virginia Byers Kraus||Qinghong Yu, Hsiao-yi Lin, Xiaomei Leng|
|The molecular epigenetics of OA genetic risk||
|Osteoarthritis - an increasing public health concern||
|10:30-12:30||Etiological research in bone and joint diseases||Osteoarthritis: a metabolic and inflammatory disease||Ali Mobasheri||Qinghong Yu, Hsiao-yi Lin, Xiaomei Leng|
|Structure, loading, and somatosensory input in the onset of OA||
|To be confirmed||
|Osteoarthritis: pathways, pain, and peripheral nerves||
|13:30-14:30||Early detection and diagnosis of bone and joint diseases||
Why X-ray is failing in OA clinical
|Lie Dai, Zhiyi Zhang|
The role of imaging in the detection and diagnosis of bone and joint diseases.
The role of imaging in the detection and diagnosis of bone and joint diseases.
|14:30-16:00||Therapeutic potentials for bone and joint diseases||
An update on the management of osteoarthritis
|Qi Li, Yifang Mei, Jianhua Xu|
Efficacy paradox and implications for clinical practice.
|Vitamin D and OA||Changhai Ding|
|16:20-17:30||Research status of bone and joint diseases in China||Osteoarthritis research by rheumatologists in China||Zhanguo Li||Cibo Huang, Yongqiang Hao, Xuewu Zhang|
|The disease burden of osteoarthritis in China|
|Bone and Joint disease research by orthopaedic surgeons in China|
|17:30-18:00||OAC Special Session||How to get a paper accepted in Osteoarthritis & Cartilage?||Joel Block||Zhanguo Li|
|08:30-10:00||Roundtable meetings with Academicians||
Zihe Rao, Kerong Dai
Zhengang Zha, Daozhang Cai, Limin Rong, Zhiyi Zhang
|10:10-11:50||Roundtable meetings with Experts in the Field||Zhanguo Li, Guanghua Lei, Jieruo Gu, Qing Jiang, Xiaochun Bai, Changhai Ding||
Anmin Jin, Lijun Lin, Shaoxiong Min,
Weiyu Han, Zhaohao Zhu, Ligang Jie
Chairs: Changhai Ding，Qi Li