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OARSI Weekly Briefing

 

Welcome to the OARSI Weekly Briefing - the single resource you need to stay up to date with OARSI & World Congress news, membership announcements, and happenings within the OARSI & OA community.

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April 9, 2021 Briefing-at-a-Glance: OARSI Live | Year in Review at OARSI Connect '21 | Research & Training Committee
Discussion Group EventsImportant Dates & Upcoming Deadlines | Past Briefings | Join / Renew

Upcoming on OARSI Live

Cell and Gene Therapy - Regenerative Medicine
April 14 @ 9:00 AM Eastern

Articular cartilage has a limited capacity for self-regeneration after injury. Repair of lesions of the articular cartilage is, therefore, a major clinical challenge. In several preclinical and clinical studies, chondrocytes and/or stem cells, delivered in suspension or seeded into biomaterials, have been shown to repair cartilage defects. In this webinar, we will learn about novel translational stem cell-mediated approaches currently under investigation for the repair of articular cartilage and the treatment of osteoarthritis.

Moderated by:
Cosimo De Bari, MD, PhD, FRCP, University of Aberdeen
Yolande F. M. Ramos, Leiden University Medical Center

Speakers:
Rocío Castro-Viñuelas, PhD, Human Movement Biomechanics (HMB)
Denis Evseenko, MD, PhD, University of Southern California
Barbara Chan, The University of Hong Kong;

 Register Now

Click here for full listing of OARSI live editions and recordings.


Annual 'Year in Review' at OARSI Connect '21

This year, just like every other, the OARSI Virtual World Congress will conclude with its 'Year in Review' session presenting research highlights from the past year.

Plenary Session 7: Year in Review
Saturday, May 1, 2021 - 5:00 PM to 7:00 PM

Meet our speakers & the topics to be covered:

OA Clinical; Epidemiology and Therapy
Jonathan Quicke, Keele University

This year in review will be a personal selection of research highlights from the 15th April 2020 to 1st April 2021. An electronic database search will be carried out in Medline and Embase focussing on OA clinical and epidemiology research carried out in human adults. Studies of perceived high clinical importance and quality or controversy in the field will be selected. Studies and findings will be grouped into emerging themes to be discussed in the final presentation. The talk will conclude with a year in review infographic.

Imaging
Edwin Oei, Erasmus Medical College

In this session I will provide a narrative review of original research publications related to imaging advancements in osteoarthritis (OA) published in the English language in the past year (May 2020-April 2021). The review will encompass a variety of imaging modalities, including radiography, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, and nuclear imaging techniques, with a focus on validation, applied human research and image analysis using novel methodology such as deep learning.

Rehabilitation & Outcomes
Michael Bade PT, DPT, PhD, University of Colorado Anschutz Medical Campus

The purpose of this presentation will be to describe recent key developments in the rehabilitative management of individuals with osteoarthritis (OA).  A review of and critique of recent literature from an evidence-based perspective will be provided.  Additionally, future directions for rehabilitation will be discussed including the need to identify subgroups of individuals with OA for targeted intervention as well as the need for strategies to promote sustainability of interventions.

Mechanics in OA
Jaap Harlaar, Professor, Delft University of Technology

This presentation will review relevant developments In mechanics in OA in 2020. This comprises both insights in the role of tissue mechanics in OA etiology as well as applications of biomechanical analyses in patient care.

Biomarkers
Yves Henrotin, PhD, University of Liège

The joint use of OMICS methods, bioinformatics and biological fluids from large patient cohorts enabled significant progress in the discovery and qualification of biological markers in osteoarthritis. This lecture is a review of the advances made in this field during the period between April 2020 and April 2021.

Genetics, Genomics, Epigenetics
David Young, PhD, Newcastle University

This presentation will summarise the year in terms of research in OA in Genetics, Genomics and Epigenetics.

OA Biology
Yangzi Jiang, PhD, The Chinese University of Hong Kong

This year in review will summarize recent interesting research on OA biology and new developed potential therapeutic targets, including the anatomical, cellular and molecular signatures, and the clinical research on regenerative therapy.

Clicking each speakers' name will bring you to more information about them.

Register Now

For registration rates and more information, visit 2021.oarsi.org.


Meet the OARSI Research & Training Committee

The Research and Training committee is responsible for the OARSi scholarships - both in establishing new means of supporting these and in selecting winners of the annual call. The committee also reviews and updates OARSI research tools on the website, helps to identify OA research gaps and suggests future directions for OA position papers from OARSI.

This committee is keen to establish new ways of supporting the training and research of OA investigators at all career stages and from all disciplines. If you have research tools (or ideas for tools) that you think could be adapted or adopted for the OA field, are passionate about a particular research gap or simply enjoy working collaboratively to further research then we'd love to hear from you.

Sarah Snelling DPhil, Committee Chair

Sarah Snelling leads the Soft Tissue Repair Group in NDORMS. She leads the CZI Tendon Seed Network and is a lecturer in Biomedicine at St Hilda's College, Oxford. 

Sarah received an MBiochem from the department of Biochemistry, University of Oxford before moving to the Botnar Research Centre, NDORMS to pursue a DPhil in the genetics and functionality of osteoarthritis.

In 2009 Sarah was awarded an Arthritis Research UK Foundation Fellowship at the University of East Anglia. Sarah returned to NDORMS in 2012 as an Arthritis Research UK Career Progression Fellow. During her fellowship Sarah interrogated the in vitro and in vivo role of the Wnt antagonist Dickkopf-3 (Dkk3) in osteoarthritis pathogenesis.  Sarah continues to work on the inflammatory and fibrotic pathways dysregulated in osteoarthritis and tendinopathy, and in understanding the cell response to biomaterial scaffolds for cartilage and tendon repair. 

Sarah is Senior Scientific Officer for the Musculoskeletal theme of the NIHR Biomedical Research Centre and is Director of taught courses for DPhil and MSc(Res) students at NDORMS. 

Committee Members

  • Don Anderson, United States
  • Mohit Kapoor, Canada
  • Jolanda Cibere, Canada
  • Alice Courties, France
  • Austine LaTourte, France
  • Margreet Kloppenberg, Netherlands
  • Michael Nevitt, United States
  • Siyi Zhu, Canada
  • Adam Culvenor, YI, Australia
  • Celeste Scotti, YI, Switzerland

To learn more about other OARSI committees and involvement opportunities at OARSI, please visit our website.


OARSI Discussion Group Events

OARSI's Discussion Groups bring together individuals with a focus on specific OA-related specialty areas. All Discussion Groups will be meeting virtually this spring, either prior to or after OARSI Connect '21. Attendance to the Discussion Group meetings is complimentary and open to anyone, whether an OARSI member or not. To view, the full list of Discussion Group events and to register, please click HERE


Important Dates & Upcoming Deadlines

  • 2021 Membership Dues: Be sure to renew your OARSI dues (or join today!). Join / Renew.
  • April 9, 2021: OARSI Connect '21 recorded presentations due. More Information.
  • April 21, 2021: OARSI Connect '21 poster/rapid fire presentations due. More information.
  • April 29  - May 1, 2021: OARSI Connect '21 (Pre-Congress programming April 28). Register today.

Download Weekly Briefing Join / Renew


Past OARSI Briefings

         

Featured Resources

OARSI White Paper- OA as a Serious Disease

By Various

Patient Summary- Non Surgical Treatment of Knee Osteoarthritis

By Multiple Authors