Welcome to the OARSI Primer

The primer is an educational tool for persons seeking to acquire basic and clinical knowledge about osteoarthritis. This includes scientists, graduate students, educators, and any training clinicians involved in OA management including Rheumatology, Orthopaedics, Primary Care and Allied Health.

Chapters include:

Epidemiology of OA- Tuhina Neogi,Joanne Jordan, Yuqing Zhang

Burden of OA- Jeffrey Katz, Elenz Losina

The Normal Synovial Joint- A. Robin Poole

Pathology of OA-Donald Salter, Joseph Buckwalter,  Linda Sandell

OA Pathogenesis

   Human Genetics- John Loughlin

Role of Obesity-Pascal Richette

Role of Mechanics-Emily McWalter, Angela Kedgley, David Wilson

Genesis of Pain-Thomas Schnitzer

Cell Signals in OA- Peter van der Kraan ,Wim van den Berg,

Chondrocyte Differentiation and OA- Martin Lotz

Inflammation and OA-Miguel Otero, Richard Loeser,  Mary Goldring

Proteinases and OA- Amanda Fosang

Experimental Models of OA-Christopher Little

Disease Diagnosis and Clinical Presentation- Michael Doherty, Abishek Abishek

Monitoring Patient Outcomes-Gillian Hawker, Aileen Davis

Imaging-Frank Roemer, Timothy Mosher,  Felix Eckstein, , Jeffrey Duryea

Biochemical Markers-J. Ch. Rousseau, Patrick Garnero

Management of OA

   Non-Pharmacologic Approach- Katherine Sanchez, Francois Rannou

   Pharmacologic Intervention- Francis Berenbaum, Jeremie Sallam

   Surgical Intervention- Glenn Wera ,Victor Goldberg

   Disease Modification-Gloria Matthews

Clinical Trial Design- Jeffrey Driban ,Tim McAlindon

 

The international scope of authors were selected on the basis of their expertise in their respective areas.  Each chapter was reviewed by another expert in the field. 

You are able to download chapters or the entire book but we ask that it be used for educational purposes only and not be reproduced.  You are also able to comment on the chapter and in this way a dialogue will be established among all the readers.

The Editors of the Primer are.

Yves Henrotin, PhD, University of Liege, Belgium

David Hunter, MBBS, PhD, University of Sydney, Sydney, Australia

Hiroshi Kawaguchi, MD, PhD, University of Tokyo, Japan

 

The Primer is free and is open access to everyone, however you will have to register one time.  Once you enter your name, institution or organization, email address, and a user name of your choice, a password will be sent to you.  You may then log in and change your password.   You will need your user name and password each time you log in.  This is NOT the same as your OARSI membership and password.