From measures to meaning: advancing OA trials to meet patients’ expectations
Publication date: Available online 30 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Jos Runhaar, Franziska Saxer, Carrie LaDuke
Osteoarthritis and Cartilage
Publisher's Note to “Cross-platform transcriptomic data integration identifies an overactive neuro-immune signature in human osteoarthritis synovium” [Osteoarthr. Cartil. 34 (2026)]
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Michael D. Newton, Hannah Swahn, Dana E. Orange, Joseph B. Lesnak, Theodore J. Price, Anne-Marie Malfait, Rachel E. Miller, Martin K. Lotz, RE-JOIN Consortium Investigators, Tristan Maerz
Cost-effectiveness of Yoga versus Strengthening Exercise for Treating Knee OA: Evidence from a Randomized Controlled Trial
Publication date: Available online 24 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Bedru J. Abafita, Ambrish Singh, Dawn Aitken, Changhai Ding, Steffany Moonaz, Andrew J. Palmer, Ting Zhao, Stan J.J. Drummen, Graeme Jones, Kim L. Bennell, Benny Antony
Bone Marrow-Derived Mesenchymal Stromal Cells Yield Greater Pain Relief and Tissue Protection than Umbilical Cord Tissue-Derived Cells in a Surgically Induced Instability Model of Osteoarthritis
Publication date: Available online 25 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Jarred Kaiser, Tracy Eng, Samir Chihab, Annie C. Bowles-Welch, Linda E. Kippner, Krishnendu Roy, Andrés J. García, Hicham Drissi
Time to wake up to the potential benefits of targeting sleep in osteoarthritis management
Publication date: Available online 22 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Michelle Hall, Paulo Ferreira, Jillian Eyles, Gillian Hawker, Simon S Smith, Natalia Egorova-Brumley, Susan M McCurry, Jonas B Thorlund, David M Klyne
Inhibition of Fibroblast Activation Protein Partially Restores the Homeostatic Phenotype of Mechanoactivated Synoviocytes
Publication date: Available online 20 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Elizabeth R. Bernstein, Brendan D. Stoeckl, Rachel Flaugh, Lorielle Laforest, Kevin G. Burt, Nathaniel A. Dyment, Carla R. Scanzello, Robert L. Mauck, Liane Miller
Scott’s parabola redux
Publication date: Available online 20 March 2026
Source: Osteoarthritis and Cartilage
Author(s): L. Stefan Lohmander
Raloxifene injections normalize age-related mechanical sensitization in female and male mice and augment intervertebral disc structure in old female mice
Publication date: Available online 19 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Neharika Bhadouria, Jonathan J. Huang, Janai Augustin, Bowen Wang, Joana I. Almeida, Tori Kroon, James Manolis, Michael Lemonick, Alan Seifert, Deepak Vashishth, James C. Iatridis, Nilsson Holguin
Screening of an FDA-approved drug library reveals MEK1/2 inhibitors block production of osteoarthritis mediators in activated human chondrocytes and synovial fibroblasts
Publication date: Available online 17 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Philip R. Coryell, Jorge G. Fernandez Davila, Adam B. Yanke, Kenneth H. Pearce, Richard F. Loeser
A CREB5-NR4A1 checkpoint protects against disc degeneration by controlling ferroptosis
Publication date: Available online 17 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Yeheng Huang, Bingru Xiao, Haibo Liang, Yuxuan Zhu, Shu Yang, Sunlong Li, Yifeng Shi, Xueqiang Wang, Xiangyang Wang
Ten year follow-up of a randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in the knee
Publication date: Available online 13 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Martyn Snow, Lee Middleton, Samir Mehta, Andrew Roberts, James Richardson, Jan Herman Kuiper, Martyn Snow, Lee Middleton, Samir Mehta., Andrew Roberts, Richard Grey, James Richardson, Jan Herman Kuiper, Steve White, Simon Roberts, David Griffiths, Aslam Mohammed, Kirti Moholkar, Tanweer Ashraf, Marcus Green
Validity of Ultrasound in Knee Osteoarthritis - A Systematic Review and Meta-analysis
Publication date: Available online 12 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Md Abu Bakar Siddiq, Vicky Duong, Jie Jia, James Linklater, Win Min Oo, David J Hunter
Generative artificial intelligence in osteoarthritis: A systematic scoping review of current applications and future directions
Publication date: Available online 11 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Jessica L. Fairley, Mohit Kapoor, Divya Sharma
PAR2 deletion in the osteoblast lineage affords long-term cartilage protection in experimental osteoarthritis
Publication date: Available online 8 March 2026
Source: Osteoarthritis and Cartilage
Author(s): C. Huesa, S. McGrath, L. Dunning, M.L. Vieri, K. McCulloch, K.A. McIntosh, T. Brown, J.J. Cole, R. Plevin, A.D. Rowan, R. van ‘t Hof, W.R. Ferrell, J.C. Lockhart, C.S. Goodyear
Utilization rates of knee arthroplasty in OECD countries revised
Publication date: Available online 6 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Jonas Backes, Christof Pabinger, Harald Lothaller, Alexander Geissler
Blind spots in reporting and representation in knee osteoarthritis research: A systematic review of the sociodemographic and clinical characteristics of 22,443 participants in randomised controlled trials of first-line care
Publication date: Available online 3 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Juanita Low, Danilo De Oliveira Silva, Allison M. Ezzat, Alison J. Gibbs, Larissa R. Souto, Moges Gashaw, Bimbi Gray, Christian J. Barton
Digital mobility measures in osteoarthritis: Endpoint innovation without losing what matters
Publication date: Available online 2 March 2026
Source: Osteoarthritis and Cartilage
Author(s): Robin Christensen, Philip Rask Lage-Hansen, Philip G. Conaghan
The associations between a diagnosis of early-stage knee osteoarthritis and the presence of MRI abnormalities in knees without radiographic osteoarthritis: Data from 1513 knees of the osteoarthritis initiative
Publication date: Available online 28 February 2026
Source: Osteoarthritis and Cartilage
Author(s): S.J.J. Drummen, D. Aitken, P. Otahal, G. Jones, S.M. Bierma-Zeinstra, J. Runhaar
Potential role of bile acids as a microbiome-derived mechanism in synovitis of knee osteoarthritis synovitis
Publication date: Available online 26 February 2026
Source: Osteoarthritis and Cartilage
Author(s): Jessica D. Murillo-Saich, Helena Mannochio-Russo, Marta Sala-Climent, Nathan Argel, Anna Quan, Michal Kalli Hose, Rocio Paz-Gonzalez, Meghana Akkati, Eric Chang, Adnan Cutuk, Emily Gentry, Roxana Coras, Nancy E. Lane, Pieter C. Dorrestein, Monica Guma
More than a prescription: The need for behavioral theory to guide exercise interventions for osteoarthritis - A narrative review
Publication date: Available online 27 February 2026
Source: Osteoarthritis and Cartilage
Author(s): Christine A. Pellegrini, Lisa C. Carlesso, Daniel K. White
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