The burden of osteoarthritis: lifespan matters
Publication date: Available online 5 November 2025
Source: Osteoarthritis and Cartilage
Author(s): Francisco AC Rocha
Osteoarthritis and Cartilage
Association of Ligament Mechanical Properties and Articular Surface Topography with Trapeziometacarpal Kinematics Across Osteoarthritis Stages
Publication date: Available online 4 November 2025
Source: Osteoarthritis and Cartilage
Author(s): Daniel Gordon, Shuchun Sun, Lizzie Walker, Nathan Buchweitz, Jichao Zhao, Eugene Mah, Claire Sumwalt, Jay Baek, Kiarra Blake-Wade, Nicholas Bain, Elizabeth Slate, Alexander Chiaramonti, Dane Daley, Hai Yao, Yongren Wu
Excessive Compression Induces Cartilage Endplate Degeneration via the Piezo1/NAT10/mTOR Signaling Axis
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Hongzhou Sun, Zhongxuan Wu, Yu Zhang, Chen Liu, Daokuan Gao, Quanlai Zhao, Liang Xiao
Osteoarthritis Year in Review 2025: Rehabilitation and outcomes including sex and gender reporting
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Andrea M Bruder, Matthew G King, Chantal M Hulshof, Harvi F Hart, Brooke E Patterson, Britt Elin Øiestad, Bjørnar Berg, Joanne L Kemp, Adam G Culvenor
Response to the Letter to the Editor: Effects of pre- and postsurgery physical activity interventions on physical activity and sedentary behavior levels following knee and hip arthroplasty: a systematic review and meta-analysis of randomized controlled…
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Noah d’Unienville, Bethany Gower, Ben Singh, Kimberley Szeto, Heather Badger, Matilda Krywanio, Carol Maher, Dominic Thewlis
Letter to the Editor concerning: T<sub>2</sub> mapping of the articular cartilage as a biomarker for knee osteoarthritis: an analysis of the population-based Rotterdam Study
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Yimei Que, Qilin Lu, Xugui Li
Intersectional Racial, Ethnic, and Sex-based Disparities in Length of Stay After Total Hip and Knee Arthroplasty: an Analysis of National Data
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Kranti C Rumalla, Sumanth R Chandrupatla, Jasvinder A Singh
Unraveling the shared genetic architecture of osteoarthritis and metabolic traits through multi-omics insights
Publication date: Available online 28 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Binzhi Liao, Yumeng Mu, Mengliang Luo, Yinjiang Liu, Qingtao Yang, Haibo Yang, Jihua Ye, Yuanyuan Wu, Feifei Cheng, Xianding Sun, Mao Nie
Artificial intelligence, machine learning and omic data integration in osteoarthritis
Publication date: Available online 28 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Divya Sharma
Pathophysiological Mechanisms Linking Osteoarthritis and Neurodegenerative Disease Risk
Publication date: Available online 28 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Pranav Prasoon, Kayla L. Nguyen, Payam A Fathi, Shruti Gupta, Sreejita Arnab, Erin Jones, Aravind Meyyappan, Elena J Stehle, John R. Bethea
Age- and sex-specific knee alignment patterns in symptomatic Korean patients: A cross-sectional deep learning analysis of 16,000 knees
Publication date: Available online 25 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Hong-Seon Lee, Se-Han Jung, Seung-hyun Song, Chaeri Park, Young Han Lee, Sung-Hwan Kim, Sangchul Hwang, Sungjun Kim
Effectiveness of exercise therapy in patients with thumb carpometacarpal osteoarthritis: A multicenter, randomized controlled trial
Publication date: Available online 23 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Robbert M. Wouters, Lisa MJ Esteban Lopez, Stella CM Heemskerk, Sita MA Bierma-Zeinstra, Gerald A. Kraan, Joost Colaris, J.Michiel Zuidam, Guus M. Vermeulen, Ruud W. Selles, the THETA Study Group Collaborators
Reply to comment on "Effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis based on large randomized trials: A systematic review and network meta-analysis"
Publication date: Available online 16 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Peter Jüni, Tiago V. Pereira, Bruno R. da Costa
Same pain, different brainstem: Sex-dependent astrocytic activation in the rostral ventromedial medulla during experimental osteoarthritis
Publication date: Available online 17 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Diana Fonseca-Rodrigues, Inês Laranjeira, Luiz Falconi-Sobrinho, Juliana Fiúza-Fernandes, Beatriz Soares, Luísa Pinto, Filipa Pinto-Ribeiro
PTHrP signalling-dependent rehabilitative effects on CD90-expressing chondrocytes
Publication date: Available online 15 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Lingfeng Xu, Yuejiao Zhang, Hongxu Yang, Jing Zhang, Qian Liu, Jiali Xu, Peinan Fan, Jia Yu, Peng Zhou, Xiaojie Xu, Wanqiu Huo, Mian Zhang, Lei Lu, Shibin Yu, Yaoping Wu, Meiqing Wang
Do rates of femorotibial cartilage loss in Kellgren-Lawrence 2 and 3 knees differ between those with mild-moderate vs. severe patellofemoral structural damage? – Data from the FNIH and IMI-APPROACH cohorts
Publication date: Available online 12 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Frank W. Roemer, Mylène Jansen, Susanne Maschek, Simon Mastbergen, Anna Wisser, Harrie H. Weinans, Francisco J. Blanco, Francis Berenbaum, Margreet Kloppenburg, Ida K. Haugen, David J. Hunter, Ali Guermazi, Wolfgang Wirth
Fibroblast and myeloid cells with high mitochondrial RNA content represent biologically significant populations within the OA synovium
Publication date: Available online 12 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Wesley Tran, Garth Blackler, Rebecca Luo, C. Thomas Appleton, Matthew W. Grol
Disparities in incident osteoarthritis between sexual minority and heterosexual adults: Findings from a large cohort study
Publication date: Available online 10 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Tingting Sha, Yilun Wang, Yuqing Zhang, Jian Zhang, Cong Lu, Jie Wei, Guanghua Lei, Chao Zeng
Dampened inflammation and reduced risk of osteoarthritis among non-industrialized societies
Publication date: Available online 8 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Ian J. Wallace, David T. Felson, Virginia B. Kraus, Tuhina Neogi, Ida K. Haugen, Janet L. Huebner, Cecilia M.T. Sena, Tracy L. Kivell, Nicholas B. Holowka, Steven Worthington, Yvonne A.L. Lim, Vivek V. Venkataraman, Thomas S. Kraft, Amanda J. Lea
Loss of peptidergic innervation of the subchondral bone in a murine model of MIA-induced osteoarthritis
Publication date: Available online 4 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Jason Ivanusic, Wendy Imlach, Jenny Thai, Jacob Bos, Jackson Hart, John-Paul Fuller-Jackson
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