Through the lens of light sheet, knee innervation shines
Publication date: Available online 25 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Frank C. Ko, Alejandro J. Almarza, Kyle D. Allen, Anne-Marie Malfait, Rachel E. Miller
Osteoarthritis and Cartilage
Effectiveness of a blended care intervention in physiotherapy with exercise and education for patients with hip or knee osteoarthritis (<em>SmArt-E</em>): a multicentre pragmatic randomized controlled trial
Publication date: Available online 29 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Franziska Weber, Corelien J.J. Kloek, Sara Neumann, Carolin Bahns, Hannes Böbinger, Freya Diederich, Valerie Dieter, Paul Gellert, Christian Kopkow, Inga Krauss, Sonia Lech, Remi Luschei, Johanna Pleus, Ute Repschläger, Heinz Rothgang, Martin Scharpenberg, Christian Thiel, Maria Valk-Draad, Cindy Veenhof, Horst Christian Vollmar
Retsat promotes synovial mesenchymal stem cell senescence and aggravates osteoarthritis by inhibiting the PPARγ/RXR heterodimerization pathway
Publication date: Available online 1 July 2026
Source: Osteoarthritis and Cartilage
Author(s): Yanbin Shi, Song Wu, Chi Liang, Li-na Zhang, Xu Cao, Junjie Huang, Wenxiu Zhang
Epidemiology of Osteoarthritis: 2026 Update of the Evidence
Publication date: Available online 6 July 2026
Source: Osteoarthritis and Cartilage
Author(s): Yvonne M. Golightly, Shamema S. Sheree, Kelli D. Allen
SMSC-EVs restore chondrocyte function through S1PR1–mTORC2–mediated mitochondrial fusion and GPS2–HDAC1–driven epigenetic regulation
Publication date: Available online 7 July 2026
Source: Osteoarthritis and Cartilage
Author(s): Zijian Guo, Xingjia Mao, Zehua Wang, Xiaoke Li, Jingkai Di, Changxin Xiang, Shuai Chen, Zehui Yan, Zui Tian, Panfeng Fu, Zigang Ge, Wenxiang Cheng, Wei Zhang, Jiake Xu, Chuan Xiang
Systemic Biomarkers of Treatment Response to Methotrexate in People with Painful Knee Osteoarthritis: a Biological Substudy of the PROMOTE Randomised Controlled Clinical Trial
Publication date: Available online 7 July 2026
Source: Osteoarthritis and Cartilage
Author(s): Jiahao Liang, Artemis Papadaki, Jennifer Alderson, Tonia L. Vincent, Philip G. Conaghan, Sarah R. Kingsbury, Fiona E. Watt
Mapping articular cartilage maturation across postnatal development by proteomics
Publication date: Available online 22 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Giulia Giuffredi, Mauro Gisbert, Karin Vancíková Filas, Jemma Falkov, Eugene T. Dillon, Sarah Moore, Margot C. Labberté, Pieter A.J. Brama, Niamh C. Nowlan
Effect of an oral complementary medicine combination for symptomatic knee osteoarthritis: A double-blind, randomized, placebo-controlled trial
Publication date: Available online 22 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Shiwen Yuan, Xiaoqian Liu, Karen Bracken, Robin Christensen, Leticia Alle Deveza, Simone Collins, Joanna E. Harnett, Andrew J. McLachlan, Sarah Robbins, Venkatesha Venkatesha, Jocelyn L. Bowden, David J. Hunter
Deep learning-based quantification of knee effusion-synovitis volume on MRI – Technique development and validation
Publication date: Available online 22 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Adrian A. Marth, Felix Liu, Ethan Pan, Brandon K.K. Fields, Gabby B. Joseph, Gabrielle Hoyer, John A. Lynch, Nancy E. Lane, Charles E. McCulloch, Michael C. Nevitt, Thomas M. Link
Multimodal characterization of articular cartilage degeneration in the humeral head using Raman spectroscopy, biomechanics, and imaging
Publication date: Available online 17 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Mason J. Garcia, Dev R. Mehrotra, Jake Giering, Erik E. Ersland, Alberto Lalli, Giovanni Intermesoli, Shubham Laiwala, Olaia Rackauskas, Mario Keko, Prateek Misra, Brian D. Snyder, Joseph P. DeAngelis, Umile Giuseppe Longo, Michael B. Albro, Arun J. Ramappa, Ara Nazarian
Adiposity and clinical outcomes of knee osteoarthritis: Sex-specific analysis from the FEAST trial
Publication date: Available online 16 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Indiana Cooper, Lynette Law, Amanda Attanayake, Joshua J. Heerey, Michael A. Girdwood, Brooke L. Devlin, Peter Brukner, Nathan P. White, Adam G. Culvenor
Erosive hand osteoarthritis is associated with increased risk of incident osteoporotic fractures in post-menopausal women (QUALYOR cohort)
Publication date: Available online 13 June 2026
Source: Osteoarthritis and Cartilage
Author(s): M.A. Auroux, A. Mercier-Guery, A. Piot, B. Merle, M. Proriol, E. Fontanges, F. Duvert, E. Lespessailles, R. Chapurlat
Structural and functional changes in articulating joints during aging of male and female C57BL/6JN mice
Publication date: Available online 12 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Manuela Oviedo, Katherine M. Arnold, Elizabeth L. Zars, Eduardo Peralta-Herrera, Samantha R. Weaver, Jennifer J. Westendorf
SESN2 Drives Osteoarthritis Progression by Inducing MFN2-Dependent Mitochondrial Hyperfusion in Rats
Publication date: Available online 1 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Yiwen Zhang, Zehang Zheng, Wenjie Hou, Chunran Pan, Kai Sun, Jiyun Li, Xiaofeng Deng, Xingru Shang, Jiawei Liu, Ruimin Chi, Xiaoxia Hao, Fengjin Guo, Tao Xu
OA Fundamentals Series: DIAGNOSIS AND CLINICAL ASSESSMENT OF OSTEOARTHRITIS
Publication date: Available online 1 June 2026
Source: Osteoarthritis and Cartilage
Author(s): Lauren K. King, Abhishek Abhishek
Deciphering the RSPO3-NFATC1 Switch in the Bone-Cartilage Paradox: Genetic Liability to Osteoporosis Protects Against Osteoarthritis by Modulating Subchondral Bone Compliance
Publication date: Available online 30 May 2026
Source: Osteoarthritis and Cartilage
Author(s): Lei Peng, Jinliang Wei, Haoran Yang, Jian Qin, Qingchu Li
Commentary; The ACTIVE trial (Snow et al.). Why did it take so long for ACI to be approved for use in the UK?
Publication date: Available online 22 May 2026
Source: Osteoarthritis and Cartilage
Author(s): Norman Waugh
GDF10 attenuates chondral fibrosis and cartilage degeneration in osteonecrosis of the femoral head: Insight into underlying regulatory mechanisms
Publication date: Available online 22 May 2026
Source: Osteoarthritis and Cartilage
Author(s): Yingkang Zhu, Wang Wei, Xu Wang, Pengbo Wang, Ruiyu Liu
A multi-switch mechanism underlying mechanical force regulation of aggrecan degradation in osteoarthritic cartilage
Publication date: Available online 22 May 2026
Source: Osteoarthritis and Cartilage
Author(s): Yen-Yu Lai, Shu-Wei Chang
Radiomics grading of hand osteoarthritis severity using standard radiographs: Results from the DIGICOD cohort
Publication date: Available online 21 May 2026
Source: Osteoarthritis and Cartilage
Author(s): Laetitia Perronne, Antoine Decoux, Loïc Duron, Constance de Margerie-Mellon, Simo Saarakkala, Emmanuel Maheu, Michel D. Crema, Anne Miquel, Francis Berenbaum, Armelle Arnoux, Jean Denis Laredo, Jérémie Sellam, Laure Fournier
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