Tribute to Dr. Frank Beier (1965–2025)
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Cheryle A. Séguin, C. Thomas Appleton
Osteoarthritis and Cartilage
Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Eva A. Bax, Roel J.H. Custers, Nienke van Egmond, Moyo C. Kruyt, Hassan Rayegan, Margreet Kloppenburg, Francisco J. Blanco, Ida K. Haugen, Francis Berenbaum, Frank W. Roemer, Harrie Weinans, Simon C. Mastbergen, Mylène P. Jansen
E1K, a disease-modifying drug candidate for knee osteoarthritis, alleviates pain and regenerates cartilage simultaneously by inhibiting TGF-β1-mediated SMAD1/5/9 signaling in osteoarthritis models
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Eun-Joung Moon, Ji Ae Kim, Yunsil Jang, Hyeon-Jeong Kim, Sang-Je Park, Cheolmin Lee, Nam Sook Kang, Hae-Jin Kim
Imeglimin, a novel antidiabetic agent related to metformin, attenuates knee osteoarthritis development and progression through AMPK activation and NF-κB signaling inhibition
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Yuki Hyodo, Yukio Akasaki, Ichiro Kurakazu, Masanari Kuwahara, Taisuke Uchida, Ryota Hirose, Mamiko Sakai, Takumi Kita, Koki Kato, Yasuharu Nakashima
Physiotherapist-led weight management for people with osteoarthritis: A scoping review
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): B. Steele-Turner, A.C. Gonçalves, A.I. Shepherd, H. Drummond, K. Allison, K.L. Bennell, T.A. Exell
Rethinking mitochondria in scRNAseq analysis
Publication date: March 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 3
Author(s): Brian Kim, Alexander J. Knights
Response to letter to the editor regarding ‘The relation of walking forces to structural damage in the knee: The Multicenter Osteoarthritis Study’
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Lauren K. Sara, David T. Felson, Michael P. LaValley, Joshua J. Stefanik, Cara L. Lewis
Transcriptomic profiling confirms microRNA-140 is more functional in joint development than in disease
Publication date: March 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 3
Author(s): Yao Hao, Hua Lin, Jamie Soul, Lynne M. Overman, Steven N. Lisgo, Jonathan Coxhead, Katarzyna A. Piróg, Ian M. Clark, Matt J. Barter, Louise N. Reynard, David A. Young
Osteoarthritis year in review 2025: Imaging
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Matthew S. Harkey, Anthony A. Gatti, Mylène P. Jansen, McKenzie S. White, Jessica Tolzman, Arjun Parmar, Ian Frederick, Thomas M. Link, Harvi F. Hart
Uncovering causal genetic mediators linking redefined obesity to osteoarthritis: Multidimensional analysis from population to genetic mechanisms
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Tengyun Yang, Chao Jia, Guoliang Wang, Wen Zhang, Boheng Zhu, Xia Li, Leijie Chen, Yanlin Li, Zhaowei Teng
Usefulness of 3D joint space width on weight-bearing CT in comparison with 2D joint space width on radiographs for predicting 24-month worsening of knee osteoarthritis pain and function in the MOST study
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Ryo Yoshikawa, Neil A. Segal, Irina Tolstykh, Michael Ho, Donald D. Anderson, John A. Lynch, Jeffrey Duryea, Michael C. Nevitt
Tribological impact of synovial fluid alterations in osteoarthritis: Correlation analyses between cartilage friction and synovial fluid properties
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Luisa de Roy, Konstantin Ambros, Graciosa Quelhas Teixeira, Jasmin Maria Bülow, Jonas Schwer, Martin Faschingbauer, Anita Ignatius, Andreas Martin Seitz
The impact of screening period pain inconsistency on placebo response in intra-articular knee osteoarthritis trials
Publication date: Available online 7 November 2025
Source: Osteoarthritis and Cartilage
Author(s): Jakob Mejdahl Bentin, Ida Sofie Adrian, Alejandro Castillo Mondragon, Andrea Bak Kaaber, Claire Prener Miller, Peter Alexandersen, Lars Arendt-Nielsen, Asger Reinstrup Bihlet
The burden of osteoarthritis: Lifespan matters
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Francisco A.C. Rocha
Association of ligament mechanical properties and articular surface topography with trapeziometacarpal kinematics across osteoarthritis stages
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Daniel Gordon, Shuchun Sun, Lizzie Walker, Nathan Buchweitz, Jichao Zhao, Eugene Mah, Claire Sumwalt, Jay Baek, Kiarra Blake-Wade, Nicholas Bain, Elizabeth Slate, Alexander Chiaramonti, Dane Daley, Hai Yao, Yongren Wu
Excessive compression induces cartilage endplate degeneration via the Piezo1/NAT10/mTOR signaling axis
Publication date: Available online 30 October 2025
Source: Osteoarthritis and Cartilage
Author(s): Hongzhou Sun, Zhongxuan Wu, Yu Zhang, Chen Liu, Daokuan Gao, Quanlai Zhao, Liang Xiao
Osteoarthritis year in review 2025: Rehabilitation and outcomes including sex and gender reporting
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Andrea M. Bruder, Matthew G. King, Chantal M. Hulshof, Harvi F. Hart, Brooke E. Patterson, Britt Elin Øiestad, Bjørnar Berg, Joanne L. Kemp, Adam G. Culvenor
Response to the Letter to the Editor: Effects of pre- and postsurgery physical activity interventions on physical activity and sedentary behavior levels following knee and hip arthroplasty: A systematic review and meta-analysis of randomized controlled…
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Noah d’Unienville, Bethany Gower, Ben Singh, Kimberley Szeto, Heather Badger, Matilda Krywanio, Carol Maher, Dominic Thewlis
Letter to the Editor concerning: T<sub>2</sub> mapping of the articular cartilage as a biomarker for knee osteoarthritis: An analysis of the population-based Rotterdam Study
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Yimei Que, Qilin Lu, Xugui Li
Intersectional racial, ethnic, and sex-based disparities in length of stay after total hip and knee arthroplasty: An analysis of national data
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Kranti C. Rumalla, Sumanth R. Chandrupatla, Jasvinder A. Singh
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