Why most responder analyses are misleading
Publication date: May 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 5
Author(s): Aleksandra Turkiewicz, Marius Henriksen, Jos Runhaar, Martin Englund
Osteoarthritis and Cartilage
Reframing early-stage symptomatic knee osteoarthritis (EsSKOA): A strategic lens for trial design
Publication date: May 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 5
Author(s): Armaghan Mahmoudian, Lauren K King, Jean W Liew, Qiuke Wang, Francis Berenbaum, Siddharth Das, Changhai Ding, Carolyn A Emery, Stephanie R Filbay, Marc C Hochberg, Muneaki Ishijima, Margreet Kloppenburg, Nancy E Lane, Elena Losina, Ali Mobasheri, C Thomas Appleton, Martin Englund, L Stefan Lohmander, Jos Runhaar, Aleksandra Turkiewicz
Sex differences in preoperative pain intensity among patients undergoing total knee arthroplasty: A propensity score–matched cross-sectional study
Publication date: May 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 5
Author(s): So Tanaka, Yuta Tomooka, Akira Mibu, Ryota Imai, Hirofumi Yamashita, Masahiro Manfuku, Keiko Yamada, Masami Tokunaga, Takaaki Yoshimoto, Takahiro Ushida, Tomohiko Nishigami
Mobile app to support home exercise adherence in knee osteoarthritis: A randomized clinical trial
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Rana S. Hinman, Rachel K. Nelligan, Penny K. Campbell, Peixuan Li, Karen E. Lamb, Sarah Stratulate, Alexander J. Kimp, Yee Foong Mok, Bridget Graham, Mark Merolli, Kim L. Bennell
Metformin and incident osteoarthritis: Causal insights from a co-twin control study
Publication date: July 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 7
Author(s): Karin Magnusson, Aleksandra Turkiewicz, Andrea Dell’Isola, Ali Kiadaliri, Martin Englund
Comprehensive zonal assessment of meniscal degeneration using quantitative UTE MRI
Publication date: July 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 7
Author(s): Arya Suprana, Mahyar Daskareh, Hee Dong Chae, Jiaji Wang, Jiyo Athertya, Soo Hyun Shin, Eric Y. Chang, Robert L. Sah, Graeme M. Bydder, Jiang Du, Yajun Ma
Osteoarthritis year in review 2025: Biology
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Fatma Scerif, Suzanne E. Eldridge
Quantitative MRI assessment of knee cartilage alterations following 60-day head-down bed rest
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Zheng Zhou, Ziyi Ren, Hao Sun, Fan Yang, Xiyang Liu, Xin Zhang, Yongzhi Li, Hongjie Huang, Jianquan Wang
Preventing osteoarthritis after anterior cruciate ligament injury: The case for targeting pre-osteoarthritis illness
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Matthew S. Harkey, Harvi F. Hart, Christopher Kuenze, Grace Lo, Virginia B. Kraus, Constance R. Chu, Jeffrey B. Driban
Immediate reductions in compressive and shear forces in the knee from gait retraining are associated with slowed cartilage degeneration after 1 year in medial knee osteoarthritis: A retrospective observational cohort study
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Kirsten Seagers, Julie A. Kolesar, Valentina Mazzoli, Eni Halilaj, Scott L. Delp, Scott D. Uhlrich
The smallest worthwhile effects of strengthening exercise on pain intensity for people with knee osteoarthritis: A benefit-harm trade-off study
Publication date: May 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 5
Author(s): Travis Haber, Kim Bennell, Harrison J. Hansford, James H. McAuley, Peter Button, Katrina Hunt, Peixuan Li, Anurika De Silva, Jesse Pardo, Sarah Stratulate, Ben Metcalf, Rana S. Hinman
Reply to the letter to the editor concerning: T<sub>2</sub> mapping of the articular cartilage as a biomarker for knee osteoarthritis: An analysis of the population-based Rotterdam Study
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Netanja I. Harlianto, Jukka Hirvasniemi, Dirk H.J. Poot, Stefan Klein, Sita M.A. Bierma-Zeinstra, Dieuwke Schiphof, Edwin H.G. Oei
Sympathosensory interactions – Possible relevance in osteoarthritis
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Zsuzsa Jenei-Lanzl, Susanne Grässel, Hans-Georg Schaible, Rainer H. Straub
Observations of early structural changes over 6 years on magnetic resonance imaging in knees without radiographic osteoarthritis
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): Karin Magnusson, Aleksandra Turkiewicz, Jaanika Paemre, Armaghan Mahmoudian, Martin Englund
Does spontaneous cartilage thickening occur in osteoarthritic knees? Data from IMI-APPROACH and the OAI
Publication date: April 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 4
Author(s): C. Salzlechner, W. Wirth, S.C. Mastbergen, M. Kloppenburg, F.J. Blanco, I.K. Haugen, F. Berenbaum, M.P. Jansen
Tribute to Dr. Frank Beier (1965–2025)
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Cheryle A. Séguin, C. Thomas Appleton
Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Eva A. Bax, Roel J.H. Custers, Nienke van Egmond, Moyo C. Kruyt, Hassan Rayegan, Margreet Kloppenburg, Francisco J. Blanco, Ida K. Haugen, Francis Berenbaum, Frank W. Roemer, Harrie Weinans, Simon C. Mastbergen, Mylène P. Jansen
E1K, a disease-modifying drug candidate for knee osteoarthritis, alleviates pain and regenerates cartilage simultaneously by inhibiting TGF-β1-mediated SMAD1/5/9 signaling in osteoarthritis models
Publication date: February 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 2
Author(s): Eun-Joung Moon, Ji Ae Kim, Yunsil Jang, Hyeon-Jeong Kim, Sang-Je Park, Cheolmin Lee, Nam Sook Kang, Hae-Jin Kim
Imeglimin, a novel antidiabetic agent related to metformin, attenuates knee osteoarthritis development and progression through AMPK activation and NF-κB signaling inhibition
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): Yuki Hyodo, Yukio Akasaki, Ichiro Kurakazu, Masanari Kuwahara, Taisuke Uchida, Ryota Hirose, Mamiko Sakai, Takumi Kita, Koki Kato, Yasuharu Nakashima
Physiotherapist-led weight management for people with osteoarthritis: A scoping review
Publication date: January 2026
Source: Osteoarthritis and Cartilage, Volume 34, Issue 1
Author(s): B. Steele-Turner, A.C. Gonçalves, A.I. Shepherd, H. Drummond, K. Allison, K.L. Bennell, T.A. Exell
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